Acuguard
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Questions & Answers
Side Effects & Adverse Reactions
Not for human use. Keep this and all drugs out of the reach of children.
Not for human use. Keep this and all drugs out of the reach of children.
Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with ACUGUARD
(see POST APPROVAL EXPERIENCE).
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
ACUGUARD kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), for one month, on cats and kittens 14 weeks of age and older and two pounds of body weight or greater.
ACUGUARD kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis) for one month, on dogs and puppies 14 weeks of age and older and 3.3 pounds of body weight or greater.
History
There is currently no drug history available for this drug.
Other Information
ACUGUARD (spinosad) is available in four sizes of chewable flavored tablets for oral administration to cats and kittens according to their weight. Each chewable flavored tablet is formulated to provide a minimum spinosad dosage of 22.5 mg/lb (50 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions 2-[(6-deoxy-2,3,4-tri-O-methyl-α-L mannopyranosyl)oxy]-13- [[5-(dimethylamino)tetrahydro-6 methyl-2H-pyran-2-yl]oxy]- 9-ethyl 2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16btetradecahydro- 14 methyl-1H-as-indaceno[3,2-d] oxacyclododecin-7,15-dione and 2 [(6-deoxy-2,3,4-tri-Omethyl- α-L-mannopyranosyl)oxy]-13-[[5 (dimethylamino) tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl 2,3,3a,5a,5b, 6,9,10,11,12,13,14,16a,16b-tetradecahydro-4,14 dimethyl- 1H-as-indaceno[3,2-d]oxacyclododecin-7,15-dione, respectively.
ACUGUARD (spinosad) is available in six sizes of chewable flavored tablets for oral administration to dogs and puppies according to their weight. Each chewable tablet is formulated to provide a minimum spinosad dosage of 13.5 mg/lb (30 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions 2-[(6 deoxy-2,3,4-tri-O-methyl-α-L-mannopyranosyl)oxy]- 13-[[5 dimethylamino)-tetrahydro-6-methyl-2H-pyran- 2-yl]oxy]-9-ethyl 2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tet radecahydro-14 methyl-1H-as-Indaceno[3,2-d]oxacyclodode cin-7, 15-dione and 2 [(6-deoxy-2,3,4-tri-O-methyl-α-Lmannopyranosyl) oxy]-13-[[5 dimethylamino)-tetrahydro-6-me thyl-2H-pyran-2-yl] oxy]-9-ethyl 2,3,3a,5a,5b,6,9,10,11,12,13, 14,16a,16b-tetradecahydro-4,14 dimethyl-1H-as- Indaceno[3,2-d] oxacyclododecin-7,15-dione, respectively.
Sources
Acuguard Manufacturers
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Vicar Operating Inc
![Acuguard (Spinosad) Tablet, Chewable [Vicar Operating Inc]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Acuguard | Vicar Operating Inc
ACUGUARD is given orally once a month, at the minimum dosage of 22.5 mg/lb (50 mg/kg).
Do not use the dosing schedule below when administering ACUGUARD to dogs, as it can result in an overdosage.
Dosage Schedule:*Cats over 24 lbs should be administered the appropriate combination of tablets.
Body Weight Spinosad Per Tablet
(mg) Tablets
Administered 2 to 4 lbs 90 One 4.1 to 6 lbs 140 One 6.1 to 12 lbs 270 One 12.1 to 24* lbs 560 OneAdminister ACUGUARD with food for maximum effectiveness.
ACUGUARD is a chewable tablet that can be consumed by cats when offered by the owner just prior to or after feeding. Alternatively, ACUGUARD may be offered in food or administered like other tablet medications. ACUGUARD should be administered at monthly intervals.
If vomiting occurs within an hour of administration, redose with another full dose. If a dose is missed, administer ACUGUARD with food and resume a monthly dosing schedule.
Treatment with ACUGUARD may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with ACUGUARD should continue the entire year without interruption.
To minimize the likelihood of flea reinfestations, it is important to treat all animals within a household with an approved flea protection product.
ACUGUARD is given orally once a month, at the recommended minimum dosage of 13.5 mg/lb (30 mg/kg).
Do not use the dosing schedule below when administering ACUGUARD to cats, as it can result in an underdosage.
Dosage Schedule:* Dogs over 120 lbs should be administered the appropriate combination of tablets.
Body Weight Spinosad Per Tablet
(mg) Tablets
Administered 3.3-4.9 lbs 90 One 5 to 10 lbs 140 One 10.1 to 20 lbs 270 One 20.1 to 40 lbs 560 One 40.1 to 60 lbs 810 One 60.1 to 120* lb 1620 OneAdminister ACUGUARD with food for maximum effectiveness.
ACUGUARD is a chewable tablet and is readily consumed by dogs when offered by the owner just prior to feeding.
Alternatively, ACUGUARD may be offered in food or administered like other tablet medications. ACUGUARD should be administered at monthly intervals.
If vomiting occurs within an hour of administration, redose with another full dose. If a dose is missed, administer ACUGUARD with food and resume a monthly dosing schedule.
Treatment with ACUGUARD may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with ACUGUARD should continue the entire year without interruption.
To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product.
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