Allergy Medicine

Allergy Medicine Manufacturers

• Stephen L. Lafrance Pharmacy, Inc.
  

  ×

  Allergy Medicine | Stephen L. Lafrance Pharmacy, Inc.

  

  ---

  take every 4 to 6 hours do not take more than 6 doses in 24 hours

  adults and children12 years
  of age and over

  1 to 2 capsules
  children 6 to under 12 years
  of age
  1 capsule
  children under 6 years of age
  

  do not use this product in
  children under 6 years of
  age

  Close
  No Recall

  More Info
• Stephen L. Lafrance Pharmacy, Inc.
  

  ×

  Allergy Medicine | Hospira, Inc.

  

  ---

  Ciprofloxacin should be administered intravenously at dosages described in the appropriate Dosage Guidelines tables.

  2.1 Dosage in Adults

  The determination of dosage and duration for any particular patient must take into consideration the severity and nature of the infection, the susceptibility of the causative microorganism, the integrity of the patient’s host-defense mechanisms, and the status of renal function.

  Table 1: Adult Dosage Guidelines 1   Due to the designated pathogens (see Indications and Usage).
  2   Used in conjunction with metronidazole.
  3   Begin administration as soon as possible after suspected or confirmed exposure.

  Infection1

  Dose

  Frequency

  Usual Duration

  Urinary Tract

  200 mg to 400 mg

  every 12 to every 8 hours

  7 to 14 days

  Lower Respiratory Tract

  400 mg

  every 12 to every 8 hours

  7 to 14 days

  Nosocomial Pneumonia

  400 mg

  every 8 hours

  10 to 14 days

  Skin and Skin Structure

  400 mg

  every 12 to every 8 hours

  7 to 14 days

  Bone and Joint

  400 mg

  every 12 to every 8 hours

  4 to 8 weeks

  Complicated Intra-Abdominal2

  400 mg

  every 12 hours

  7 to 14 days

  Acute Sinusitis

  400 mg

  every 12 hours

  10 days

  Chronic Bacterial Prostatitis

  400 mg

  every 12 hours

  28 days

  Empirical Therapy In Febrile
  Neutropenic Patients

  Ciprofloxacin

  400 mg

  and

  Piperacillin

  50 mg/kg

   

  every 8 hours

  ___________

  every 4 hours

  7 to 14 days

  Inhalational anthrax (post-exposure)3

  400 mg

  every 12 hours

  60 days

  Plague3

  400 mg

  every 12 to 8 hours

  14 days

  Conversion of Intravenous to Oral Dosing in Adults

  Patients whose therapy is started with ciprofloxacin injection may be switched to CIPRO Tablets or Oral Suspension when clinically indicated at the discretion of the physician (Table 2) [see Clinical Pharmacology (12.3)].

  Table 2: Equivalent AUC Dosing Regimens

  Ciprofloxacin Oral Dosage

  Equivalent Ciprofloxacin Injection Dosage

  250 mg Tablet every 12 hours

  200 mg intravenous every 12 hours

  500 mg Tablet every 12 hours

  400 mg intravenous every 12 hours

  750 mg Tablet every 12 hours

  400 mg intravenous every 8 hours

  2.2 Dosage in Pediatric Patients

  Dosing and initial route of therapy (that is, IV or oral) for cUTI or pyelonephritis should be determined by the severity of the infection.

  Table 3: Pediatric Dosage Guidelines 1   The total duration of therapy for cUTI and pyelonephritis in the clinical trial was determined by the physician. The mean duration of treatment was 11 days (range 10 to 21 days).
  2   Begin drug administration as soon as possible after suspected or confirmed exposure.
  3   Begin drug administration as soon as possible after suspected or confirmed exposure to Y. pestis.

  Infection

  Route of Administration

  Dose (mg/kg)

  Frequency

  Total Duration

  Complicated Urinary Tract or Pyelonephritis (patients from 1 to 17 years of age)1

  Intravenous

  6 mg/kg to 10 mg/kg (maximum 400 mg per dose; not to be exceeded even in patients weighing >51 kg)

  Every 8 hours

  10 to 21 days1

  Inhalational Anthrax

  (Post-Exposure)2

  Intravenous

  10 mg/kg

  (maximum 400 mg per dose)

  Every 12 hours

  60 days

  Plague2,3

  Intravenous

  10 mg/kg

  (maximum 400 mg per dose)

  Every 12 to 8 hours

  10 to 21 days

  2.3 Dosage Modifications in Patients with Renal Impairment

  Ciprofloxacin is eliminated primarily by renal excretion; however, the drug is also metabolized and partially cleared through the biliary system of the liver and through the intestine. These alternative pathways of drug elimination appear to compensate for the reduced renal excretion in patients with renal impairment. Nonetheless, some modification of dosage is recommended, particularly for patients with severe renal dysfunction. Dosage guidelines for use in patients with renal impairment are shown in Table 4.

  Table 4: Recommended Starting and Maintenance Doses for Adult Patients with Impaired Renal Function

  Creatinine Clearance (mL/min)

  Dose

  > 30

  See Usual Dosage

  5 to 29

  200 to 400 mg every 18 to 24 hours

  When only the serum creatinine concentration is known, the following formulas may be used to estimate creatinine clearance:

  Men - Creatinine clearance (mL/min) = Weight (kg) x (140 – age)
                                                              72 x serum creatinine (mg/dL)

  Women - 0.85 x the value calculated for men.

  The serum creatinine should represent a steady state of renal function.

  In patients with severe infections and severe renal impairment and hepatic insufficiency, careful monitoring is suggested.

  Pediatric patients with moderate to severe renal insufficiency were excluded from the clinical trial of cUTI and pyelonephritis. No information is available on dosing adjustments necessary for pediatric patients with moderate to severe renal insufficiency (that is, creatinine clearance of < 50 mL/min/1.73m2).

  2.4 Preparation of Ciprofloxacin for Administration

  The 2 mg/mL infusion solution in 5% dextrose is available in flexible containers of 100 mL or 200 mL. The solutions in flexible containers do not need to be diluted and may be infused as described below.

  If the Y-type or “piggyback” method of administration is used, it is advisable to discontinue temporarily the administration of any other solutions during the infusion of ciprofloxacin. If the concomitant use of ciprofloxacin and another drug is necessary each drug should be given separately in accordance with the recommended dosage and route of administration for each drug.

  2.5 Important Administration Instructions

  Intravenous Infusion

  Ciprofloxacin should be administered to by intravenous infusion over a period of 60 minutes. Slow infusion of a dilute solution into a larger vein will minimize patient discomfort and reduce the risk of venous irritation.

  Hydration of Patients Receiving Ciprofloxacin

  Adequate hydration of patients receiving ciprofloxacin should be maintained to prevent the formation of highly concentrated urine. Crystalluria has been reported with quinolones [see Warnings and Precautions (5.12), Adverse Reactions (6.1), Nonclinical Toxicology (13.2) and Patient Counseling Information (17)].

  Close
  No Recall

  More Info
• Stephen L. Lafrance Pharmacy, Inc.
  

  ×

  Allergy Medicine | Stephen L. Lafrance Pharmacy, Inc.

  

  ---

  take every 4 to 6 hours

  do not take more than 6 doses in 24 hours

  adults and children 12 years of age and over  1 to 2 tablets   children 6 to under 12 years of age  1 tablet  children under 6 years of age  do not use this product in children under 6 years of age

  Close
  No Recall

  More Info
• Costco Wholesale Corporation
  

  ×

  Allergy Medicine | Sandoz Inc

  

  ---

  Amoxicillin and clavulanate potassium for oral suspension, USP does not contain the same amount of clavulanic acid (as the potassium salt) as any of the other suspensions of amoxicillin and clavulanate potassium. Amoxicillin and clavulanate potassium for oral suspension, USP contains 42.9 mg of clavulanic acid per 5 mL, whereas the 200 mg/5 mL suspension of amoxicillin and clavulanate potassium contains 28.5 mg of clavulanic acid per 5 mL and the 400 mg/5 mL suspension contains 57 mg of clavulanic acid per 5 mL. Therefore, the 200 mg/28.5 mg per 5 mL and 400 mg/57 mg per 5 mL suspensions of amoxicillin and clavulanate potassium should notbe substituted for amoxicillin and clavulanate potassium for oral suspension, USP as they are not interchangeable.

  Dosage

  Pediatric Patients 3 Months and Older

  Based on the amoxicillin component (600 mg per 5 mL), the recommended dose of amoxicillin and clavulanate potassium for oral suspension, USP is 90 mg/kg/day divided every 12 hours, administered for 10 days (see chart below). This dose provides 6.4 mg/kg/day of the clavulanic acid component.

  Body Weight (kg)

  Volume of Amoxicillin and Clavulanate Potassium for Oral Suspension, USP Providing 90 mg/kg/day

  8

  3 mL twice daily

  12

  4.5 mL twice daily

  16

  6 mL twice daily

  20

  7.5 mL twice daily

  24

  9 mL twice daily

  28

  10.5 mL twice daily

  32

  12 mL twice daily

  36

  13.5 mL twice daily

  Pediatric Patients Weighing 40 kg and More 

  Experience with amoxicillin and clavulanate potassium for oral suspension, USP in this group is not available.

  Adults

  Experience with amoxicillin and clavulanate potassium for oral suspension, USP in adults is not available and adults who have difficulty swallowing should not be given amoxicillin and clavulanate potassium for oral suspension, USP in place of the 500-mg or 875-mg tablet of amoxicillin and clavulanate potassium.

  Hepatically impaired patients should be dosed with caution and hepatic function monitored at regular intervals (see WARNINGSAND PRECAUTIONS(5).

  Directions for Mixing Oral Suspension  

  Prepare a suspension at time of dispensing as follows: Tap bottle until all the powder flows freely. Add approximately 2/3 of the total amount of water for reconstitution (see table below) and shake vigorously to suspend powder. Add remainder of the water and again shake vigorously.

  Amoxicillin and Clavulanate Potassium for Oral Suspension

  Amoxicillin and Clavulanate Potassium for Oral Suspension

  Bottle Size

  Amount of Water Required for Reconstitution

  75 mL

  62 mL

  125 mL

  103 mL

  200 mL

  165 mL

  Each teaspoonful (5 mL) will contain 600 mg amoxicillin as the trihydrate and 42.9 mg of clavulanic acid as the potassium salt.

  NOTE: SHAKE ORAL SUSPENSION WELL BEFORE USING.

  Administration

  To minimize the potential for gastrointestinal intolerance, Amoxicillin and  Clavulanate Potassium for Oral Suspension, USP should be taken at the start of a meal. Absorption of clavulanate potassium may be enhanced when Amoxicillin and  Clavulanate Potassium for Oral Suspension, USP is administered at the start of a meal.

  Close
  No Recall

  More Info