Dexium
Loading...Dexium Recall
Get an alert when a recall is issued.
Questions & Answers
Side Effects & Adverse Reactions
WARNINGS: Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis.
Additionally, corticosteroids administered to dogs, rabbits, and rodents, during pregnancy have produced cleft palate. Other congenital anomalies including deformed forelegs, phocomelia, and anasarca have been reported in offspring of dogs which received corticosteroids during pregnancy.
A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.
SIDE EFFECTS: Side effects, such as SAP and SGPT enzyme elevations, weight loss, anorexia, polydipsia, and polyuria, have occurred following corticosteroids in dogs. Vomiting and diarrhea (occassionally bloody) have been observed in cats and dogs. Cushing's syndrome in dogs has been reported in association with prolonged or repeated steroid therapy. Corticosteroids reportedly cause laminitis in horses.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
INDICATIONS: Dexium is indicated for the treatment of primary bovine ketosis and as an anti-inflammatory agent in the bovine and equine. As supportive therapy, Dexium may be used in the management of various rheumatic, allergic, dermatologic, and other diseases known to be responsive to anti-inflammatory corticosteroids. Dexium may be used intravenously as supportive therapy when an immediate hormonal response is required.
Bovine Ketosis: Dexium is offered for the treatment of primary ketosis. The gluconeogenic effects of Dexium, when administered intramuscularly, are generally noted within the first 6 to 12 hours. When Dexium is used intravenously, the effects may be noted sooner. Blood sugar levels rise to normal levels rapidly and generally rise to above normal levels within 12 to 24 hours. Acetone bodies are reduced to normal concentrations usually within 24 hours. The physical attitude of animals treated with Dexium brightens and appetite improves, usually within 12 hours. Milk production, which is suppressed as a compensatory reaction in this condition, begins to increase. In some instances, it may even surpass previous peaks. The recovery process usually takes from 3 to 7 days.
Supportive Therapy: Dexium may be used as supportive therapy in mastitis, metritis, traumatic gastritis, and pyelonephritis, while appropriate primary therapy is administered. In these cases, the corticosteroid combats accompanying stress and enhances the feeling of general well-being. Dexium may also be used as supportive therapy in inflammatory conditions such as arthritic conditions, snake bite, acute mastitis, shipping fever, pneumonia, laminitis, and retained placenta.
Equine: Dexium is indicated for the treatment of acute musculoskeletal inflammations, such as bursitis, carpitis, osselets, tendonitis, myositis, and sprains. If boney changes exist in any of these conditions, joints or accessory structures, a response to Dexium cannot be expected. In addition, Dexium may be used as supportive therapy in fatigue, heat exhaustion, influenza, laminitis, and retained placenta provided that the primary cause is determined and corrected.
History
There is currently no drug history available for this drug.
Other Information
DESCRIPTION: Dexamethasone Solution is a synthetic analogue of prednisolone, having similar but more potent anti-inflammatory therapeutic action and diversified hormonal and metabolic effects. Modification of the basic corticoid structure as achieved in Dexium offers enhanced anti-inflammatory effect compared to older corticosteroids. The dosage of Dexium required is markedly lower than that of prednisone and prednisolone. Dexium is not species-specific; however, the veterinarian should read the sections on INDICATIONS, DOSAGE, SIDE EFFECTS, CONTRAINDICATIONS, PRECAUTIONS, and WARNINGS before this drug is used. Dexium is intended for intravenous or intramuscular administration. Each mL contains 2 mg dexamethasone, 500 mg polyethylene glycol 400, 9 mg benzyl alcohol, 1.8 mg methylparaben and 0.2 mg propylparaben as preservatives, 4.75% alcohol, HCl to adjust pH to approximately 4.9, water for injection q.s.
Sources
Dexium Manufacturers
-
Bimeda, Inc. Division Of Cross Vetpharm Group
![Dexium (Dexamethasone) Injection, Solution [Bimeda, Inc. Division Of Cross Vetpharm Group]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Dexium | Bimeda, Inc. Division Of Cross Vetpharm Group
ADMINISTRATION AND DOSAGE: Therapy with Dexium®, as with any other potent corticosteroid, should be individualized according to the severity of the condition being treated, anticipated duration of steroid therapy, and animal's threshold or tolerance for steroid excess. Treatment may be changed over to Dexium® from any other glucocorticoid with proper reduction or adjustment of doage.
Bovine:Dexium®: 5 - 20 mg intravenously or intramuscularly.
Equine:Dexium®: 2.5 - 5 mg intravenously or intramuscularly.
-
Bimeda, Inc. Division Of Cross Vetpharm Group
Dexium | Bimeda, Inc. Division Of Cross Vetpharm Group
DOSAGE AND ADMINISTRATION: Dosage and administration for Dexium Tablets are as follows:
Dogs: Administer orally at 0.25 to 1.25 mg. per day up to 7 days
Cats: Administer orally at 0.125 to 0.5 mg. per day up to 7 days
![Dexium (Dexamethasone) Tablet [Bimeda, Inc. Division Of Cross Vetpharm Group]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=0a9cb1f4-cfaa-42a9-aa59-46a6092b6ffc&name=label.jpg)
Login To Your Free Account