Good Sense Cold Multi Symptom
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Questions & Answers
Side Effects & Adverse Reactions
In a few patients hydralazine may produce a clinical picture simulating systemic lupus erythematosus including glomerulonephritis. In such patients hydralazine should be discontinued unless the benefit-to-risk determination requires continued antihypertensive therapy with this drug. Symptoms and signs usually regress when the drug is discontinued but residua have been detected many years later. Long-term treatment with steroids may be necessary. (See PRECAUTIONS, Laboratory Tests.)
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
Severe essential hypertension when the drug cannot be given orally or when there is an urgent need to lower blood pressure.
History
There is currently no drug history available for this drug.
Other Information
Hydralazine Hydrochloride Injection, USP is an antihypertensive available in a 1 mL vial for intravenous and intramuscular administration. Each milliliter of the sterile, nonpyrogenic colorless solution contains Hydralazine Hydrochloride USP, 20 mg, Propylene Glycol USP, 103.6 mg, and Water for Injection q.s. The pH of the solution is 3.4 - 4.4. pH may be adjusted with Hydrochloric Acid and/or Sodium Hydroxide. Hydralazine Hydrochloride is 1-Hydrazinophthalazine monohydrochloride, and its structural formula is:
structure
Molecular Formula C8H8N4HCl
Hydralazine Hydrochloride USP is a white to off-white, odorless crystalline powder. It is soluble in water, slightly soluble in alcohol, and very slightly soluble in ether. It melts at about 275°C, with decomposition, and has a molecular weight of 196.64.
Sources
Good Sense Cold Multi Symptom Manufacturers
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L Perrigo Company
![Good Sense Cold Multi Symptom (Acetaminophen, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride) Tablet, Film Coated [L Perrigo Company]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Good Sense Cold Multi Symptom | X-gen Pharmaceuticals, Inc.
When there is urgent need, therapy in the hospitalized patient may be initiated intramuscularly or as a rapid intravenous bolus injection directly into the vein. Hydralazine hydrochloride injection should be used only when the drug cannot be given orally. The usual dose is 20-40 mg, repeated as necessary.
Certain patients (especially those with marked renal damage) may require a lower dose. Blood pressure should be checked frequently. It may begin to fall within a few minutes after injection, with the average maximal decrease occurring in 10-80 minutes. In cases where there has been increased intracranial pressure, lowering the blood pressure may increase cerebral ischemia. Most patients can be transferred to oral hydralazine hydrochloride within 24-48 hours.
The product should be used immediately after the vial is opened. It should not be added to infusion solutions. Hydralazine hydrochloride injection may discolor upon contact with metal; discolored solutions should be discarded.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
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L. Perrigo Company
Good Sense Cold Multi Symptom | L. Perrigo Company
• do not take more than directed (see Liver warning)adults and children 12 years and over
• take 2 caplets every 4 hours • swallow whole – do not crush, chew or dissolve • do not take more than 10 caplets in 24 hourschildren under 12 years
ask a doctor
![Good Sense Cold Multi Symptom (Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride) Tablet, Film Coated [L. Perrigo Company]](http://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=2e6eaa26-f297-46c8-8a25-6f98d9f96ee7&name=d5fd1911-e247-498b-a4ca-702e50d66542-01.jpg)
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