Ketacine
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Questions & Answers
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Uses
INDICATIONS
Ketacine™ may be used in cats for restraint or as the sole anesthetic agent for diagnostic or minor, brief, surgical procedures that do not require skeletal muscle relaxation. It may be used in subhuman primates for restraint.
History
There is currently no drug history available for this drug.
Other Information
DESCRIPTION
Ketacine™ is a rapid-acting, nonnarcotic, nonbarbiturate agent for anesthetic use in cats and for restraint in subhuman primates. It is chemically designated dl2-(o-chlorophenyl)-2-(methylamino) cyclohexanone hydrochloride and is supplied as a slightly acid (pH 3.5 to 5.5) solution for intramuscular injection in a concentration containing the equivalent of 100 mg ketamine base per milliliter and contains not more than 0.1 mg/mL benzethonium chloride as a preservative.
Sources
Ketacine Manufacturers
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Mwi/vetone
![Ketacine (Ketamine Hydrochloride) Injection, Solution [Mwi/vetone]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Ketacine | Mwi/vetone
DOSAGE AND ADMINISTRATION
Ketacine™ is well tolerated by cats and subhuman primates when administered by intramuscular injection.
Fasting prior to induction of anesthesia or restraint with Ketacine™ is not essential; however, when preparing for elective surgery, it is advisable to withhold food for at least six hours prior to administration of Ketacine™.
Anesthesia may be of shorter duration in immature cats. Restraint in subhuman primate neonates (less than 24 hours of age) is difficult to achieve.
As with other anesthetic agents, the individual response to Ketacine™ is somewhat varied depending upon the dose, general condition and age of the subject so that dosage recommendations cannot be absolutely fixed.
Dosage
Cats: A dose of 11 mg/kg (5 mg/lb) is recommended to produce restraint. Dosages from 22 to 33 mg/kg (10 to 15 mg/lb) produce anesthesia that is suitable for diagnostic or minor surgical procedures that do not require skeletal muscle relaxation.
Subhuman Primates: The recommended restraint dosages of Ketacine™ for the following species are: Cercocebus torquatus (white-collared mangabey), Papio cynocephalus (yellow baboon), Pantroglodytes verus (chimpanzee), Papio anubis (olive baboon), Pongo pygmaeus (orangutan), Macaca nemestrina (pig-tailed macaque) 5 to 7.5 mg/kg; Presbytis entellus (entellus langur) 3 to 5 mg/kg; Gorilla gorilla gorilla (gorilla) 7 to 10 mg/kg; Aotus trivirgatus (night monkey) 10 to 12 mg/kg; Macaca mulatta (rhesus monkey) 5 to 10 mg/kg; Cebus capucinus (white-throated capuchin) 13 to 15 mg/kg; and Macaca fascicularis (crab-eating macaque), Macaca radiata (bonnet macaque) and Saimiri sciureus (squirrel monkey) 12 to 15 mg/kg.A single intramuscular injection produces restraint suitable for TB testing; radiography, physical examination or blood collection.
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