FDA records indicate that there are no current recalls for this drug.
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Questions & Answers
Side Effects & Adverse Reactions
There is currently no warning information available for this product. We apologize for any inconvenience.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
NAMZARIC is indicated for the treatment of moderate to severe dementia of the Alzheimer's type in patients stabilized on:
- memantine hydrochloride (10 mg twice daily or 28 mg extended-release once daily) and donepezil hydrochloride 10 mg.
- memantine hydrochloride (5 mg twice daily or 14 mg extended-release once daily) and donepezil hydrochloride 10 mg (in patients with severe renal impairment).
History
There is currently no drug history available for this drug.
Other Information
NAMZARIC capsules contain memantine, an orally active NMDA receptor antagonist, as the hydrochloride salt and donepezil, a reversible inhibitor of the enzyme acetylcholinesterase, as the hydrochloride salt.
Memantine Hydrochloride
The chemical name for memantine hydrochloride is 1-amino-3,5-dimethyladamantane hydrochloride with the following structural formula:
The molecular formula is C12H21N•hydrochloride and the molecular weight is 215.76. Memantine hydrochloride occurs as a fine white to off-white powder.
Donepezil Hydrochloride
The chemical name for donepezil hydrochloride is 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride.
The molecular formula is C24H29NO3•hydrochloride and the molecular weight is 415.96. Donepezil hydrochloride is a white crystalline powder.
NAMZARIC
NAMZARIC is provided as capsules for oral administration, containing 14 mg memantine hydrochloride extended-release and 10 mg donepezil hydrochloride (14 mg/10 mg) or 28 mg memantine hydrochloride extended-release and 10 mg donepezil hydrochloride (28 mg/10 mg).
All doses of NAMZARIC contain the following inactive ingredients: sugar spheres, povidone, talc, hypromellose, polyethylene glycol, ethylcellulose, oleic acid, medium chain triglycerides, lactose monohydrate, microcrystalline cellulose, corn starch, colloidal silicon dioxide, and magnesium stearate. The hard gelatin capsules contain titanium dioxide, gelatin, shellac glaze, and black iron oxide; colorants are FD&C Blue 1 (28mg/10mg) and FD&C Blue 1 and yellow iron oxide (14 mg/10 mg).
Sources
Medique Back Pain Off Manufacturers
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Unifirst First Aid Corporation
Medique Back Pain Off | Personal Care Products, Inc.
wash affected area and dry thoroughly shake can well and spray a this layer over affected area twice daily (morning and night) supervise children in the use of this product for athlete's foot: pay special attention to the spaces between the toes, wear well-fitting, ventilated shoes and change shoes and socks at least once day. use daily for 4 weeks; if condition persists longer, consult a doctor to prevent athlete's foot, apply once or twice daily (morning and night) in case of clogging, clean nozzle with a pin
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