Mega-c-acid Plus
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Questions & Answers
Side Effects & Adverse Reactions
WARNINGS:
Diabetics, patients prone to recurrent renal calculi, those undergoing stool occult blood tests and those on sodium restricted diets or anticoagulant therapy should not take excessive doses of ascorbic acid over an extended period of time.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
INDICATIONS AND USAGE:
Ascorbic acid is recommended for the prevention and treatment of scurvy. Its parenteral administration is desirable for patients with an acute deficiency or for those whose absorption of orally ingested ascorbic acid is uncertain.
Symptoms of mild deficiency may include faulty bone and tooth development, gingivitis, bleeding gums, and loosened teeth. Febrile states, chronic illness and infection (pneumonia, whooping cough, tuberculosis, diphtheria, sinusitis, rheumatic fever, etc) increase the need for ascorbic acid.
Hemovascular disorders, burns, delayed fracture and wound healing are indicators for an increase in the daily intake.
History
There is currently no drug history available for this drug.
Other Information
DESCRIPTION:
Ascorbic Acid (Vitamin C) is a water-soluble vitamin. It occurs as a white or slightly yellow crystal or powder with a light acidic taste. It is an antiscorbutic product. On exposure to air it gradually darkens. In the dry state it is reasonable stable in air, but in solution it rapidly oxidizes. Ascorbic Acid is freely soluble in water, sparingly soluble in alcohol; insoluble in chloroform, ether and benzene.
The chemical name of Ascorbic Acid is L-ascorbic acid. The molecular formula is C6H8O6 and the molecular weight is 176.13.
Ascorbic Acid injection is a clear, colorless to slightly yellow sterile solution of Ascorbic Acid in Water for Injection, for intravenous, intramuscular or subcutaneous use. Each ml contains: Accorbic Acid 500 mg, Disodium Edetate 0.25mg, Sodium Hydroxide 110mg, in Water for Injection q.s. pH (range 5.5-7.0) adjusted with Sodium Bicarbonate and Sodium Hydroxide. Contains no preservatives.
Sources
Mega-c-acid Plus Manufacturers
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Merit Pharmaceutical
![Mega-c-acid Plus (Ascorbic Acid) Injection, Solution [Merit Pharmaceutical]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Mega-c-acid Plus | Merit Pharmaceutical
DOSAGE AND ADMINISTRATION:
Ascorbic Acid is usually administered orally. When oral administration is not feasible or when malabsorption is suspected, the drug may be administered intramuscularly, intravenously or subcutaneously. When given parenterally, utilization of the vitamin is best after IM administration which is the preferred parenteral route.
For intravenous injection, dilution into a large volume parenteral such as Normal Saline or Glucose is recommended to minimize the adverse reactions associated with intravenous injection.
The average protective dose of ascorbic acid for adults is 70 to 150 mg daily. In the presence of scurvy, doses of 300 mg to 1 gram daily are recommended. However, as much as 6 grams have been administered parenterally to normal adults without the evidence of toxicity.
To enhance wound healing, doses of 300 to 500 mg daily for a week to 10 days, both preoperatively and postoperatively, are generally considered adequate, although considerably larger amounts have been recommended. In the treatment of burns, doses are governed by the extent of tissue injury. For severe burns, daily doses of 1 to 2 grams are recommended. In other conditions in which the need for ascorbic acid is increased, three to five times the daily optimum allowances appear to be adequate.
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