Methocarbamol

Methocarbamol

Methocarbamol Recall

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Questions & Answers

Side Effects & Adverse Reactions

Since methocarbamol may possess a general CNS depressant effect, patients receiving methocarbamol tablets should be cautioned about combined effects with alcohol and other CNS depressants.

Safe use of methocarbamol has not been established with regard to possible adverse effects upon fetal development. There have been reports of fetal and congenital abnormalities following in utero exposure to methocarbamol. Therefore, methocarbamol tablets should not be used in women who are or may become pregnant and particularly during early pregnancy unless in the judgment of the physician the potential benefits outweigh the possible hazards (see PRECAUTIONS, Pregnancy).

Use In Activities Requiring Mental Alertness

Methocarbamol may impair mental and/or physical abilities required for performance of hazardous tasks, such as operating machinery or driving a motor vehicle. Patients should be cautioned about operating machinery, including automobiles, until they are reasonably certain that methocarbamol therapy does not adversely affect their ability to engage in such activities.

Legal Issues

There is currently no legal information available for this drug.

FDA Safety Alerts

There are currently no FDA safety alerts available for this drug.

Manufacturer Warnings

There is currently no manufacturer warning information available for this drug.

FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.

Uses

Methocarbamol is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of methocarbamol has not been clearly identified, but may be related to its sedative properties. Methocarbamol does not directly relax tense skeletal muscles in man.

History

There is currently no drug history available for this drug.

Other Information

Methocarbamol Tablets USP, 500 mg and 750 mg, a carbamate derivative of guaifenesin, is a central nervous system (CNS) depressant with sedative and musculoskeletal relaxant properties.

The chemical name of methocarbamol is 3-(2-methoxyphenoxy)-1, 2-propanediol 1-carbamate and has the empirical formula C11H15NO5. Its molecular weight is 241.24. The structural formula is shown below.

Chemical Structure

Methocarbamol is a white powder, sparingly soluble in water and chloroform, soluble in alcohol (only with heating) and propylene glycol, and insoluble in benzene and n-hexane.

Methocarbamol tablet, 500 mg is available as an orange, film coated, round convex tablet containing 500 mg of methocarbamol, USP for oral administration. The inactive ingredients present are microcrystalline cellulose, croscarmellose sodium, FD&C Yellow 6 aluminum lake, hydroxypropyl cellulose, hypromellose, magnesium stearate, polyethylene glycol, triacetin, titanium dioxide.

Methocarbamol tablet, 750 mg is available as a yellow, film coated, modified capsule shaped tablet containing 750 mg of methocarbamol, USP for oral administration. The inactive ingredients present are microcrystalline cellulose, croscarmellose sodium, iron oxide yellow, iron oxide red, hydroxypropyl cellulose, hypromellose, magnesium stearate, polyethylene glycol, triacetin, titanium dioxide.

Methocarbamol Manufacturers


  • Virtus Pharmaceuticals
    Methocarbamol Tablet, Film Coated [Virtus Pharmaceuticals]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • Kaiser Foundation Hospitals
    Methocarbamol Tablet [Kaiser Foundation Hospitals]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • Blenheim Pharmacal, Inc.
    Methocarbamol Tablet [Blenheim Pharmacal, Inc.]
  • Preferred Pharmaceuticals, Inc.
    Methocarbamol Tablet [Preferred Pharmaceuticals, Inc.]
  • Preferred Pharmaceuticals, Inc.
    Methocarbamol Tablet [Preferred Pharmaceuticals, Inc.]
  • Avpak
    Methocarbamol (Methocarbamol) Tablet [Avpak]
  • Lannett Company, Inc.
    Methocarbamol (Methocarbamol) Tablet [Lannett Company, Inc.]
  • Hetero Drugs Limited Unit Iii
    Methocarbamol Tablet [Hetero Drugs Limited Unit Iii]
  • Watson Laboratories, Inc.
    Methocarbamol Tablet [Watson Laboratories, Inc.]
  • Qualitest Pharmaceuticals
    Methocarbamol Tablet [Qualitest Pharmaceuticals]
  • Keltman Pharmaceuticals Inc.
    Methocarbamol Tablet [Keltman Pharmaceuticals Inc.]
  • Major Pharmaceuticals
    Methocarbamol Tablet [Major Pharmaceuticals]
  • Contract Pharmacy Services-pa
    Methocarbamol Tablet [Contract Pharmacy Services-pa]
  • Blenheim Pharmacal, Inc.
    Methocarbamol Tablet [Blenheim Pharmacal, Inc.]
  • Lake Erie Medical Dba Quality Care Products Llc
    Methocarbamol Tablet [Lake Erie Medical Dba Quality Care Products Llc]
  • Contract Pharmacy Services-pa
    Methocarbamol Tablet [Contract Pharmacy Services-pa]
  • Kaiser Foundation Hospitals
    Methocarbamol Tablet [Kaiser Foundation Hospitals]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • Rebel Distributors Corp.
    Methocarbamol Tablet [Rebel Distributors Corp.]
  • Pd-rx Pharmaceuticals, Inc.
    Methocarbamol (Methocarbamol) Tablet [Pd-rx Pharmaceuticals, Inc.]
  • Pd-rx Pharmaceuticals, Inc.
    Methocarbamol Tablet [Pd-rx Pharmaceuticals, Inc.]
  • Lake Erie Medical & Surgical Supply Dba Quality Care Products Llc
    Methocarbamol Tablet [Lake Erie Medical & Surgical Supply Dba Quality Care Products Llc]
  • Lake Erie Medical Dba Quality Care Products Llc
    Methocarbamol Tablet [Lake Erie Medical Dba Quality Care Products Llc]
  • H.j. Harkins Company, Inc.
    Methocarbamol Tablet [H.j. Harkins Company, Inc.]
  • American Health Packaging
    Methocarbamol Tablet [American Health Packaging]
  • Physicians Total Care, Inc.
    Methocarbamol Tablet [Physicians Total Care, Inc.]
  • Stat Rx Usa Llc
    Methocarbamol Tablet [Stat Rx Usa Llc]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • Rebel Distributors Corp
    Methocarbamol Tablet [Rebel Distributors Corp]
  • Ncs Healthcare Of Ky, Inc Dba Vangard Labs
    Methocarbamol Tablet [Ncs Healthcare Of Ky, Inc Dba Vangard Labs]
  • Unit Dose Services
    Methocarbamol Tablet [Unit Dose Services]
  • Lake Erie Medical & Surgical Supply Dba Quality Care Products Llc
    Methocarbamol Tablet [Lake Erie Medical & Surgical Supply Dba Quality Care Products Llc]
  • Stat Rx Usa Llc
    Methocarbamol Tablet [Stat Rx Usa Llc]
  • Aphena Pharma Solutions – Tennessee, Inc.
    Methocarbamol Tablet [Aphena Pharma Solutions – Tennessee, Inc.]
  • Aidarex Pharmaceuticals Llc
    Methocarbamol Tablet [Aidarex Pharmaceuticals Llc]
  • Bryant Ranch Prepack
    Methocarbamol Tablet [Bryant Ranch Prepack]
  • Bryant Ranch Prepack
    Methocarbamol Tablet [Bryant Ranch Prepack]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • Solco Healthcare Us Llc
    Methocarbamol Tablet [Solco Healthcare Us Llc]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc.]
  • Bryant Ranch Prepack
    Methocarbamol Tablet [Bryant Ranch Prepack]
  • Pd-rx Pharmaceuticals, Inc.
    Methocarbamol Tablet [Pd-rx Pharmaceuticals, Inc.]
  • Camber Pharmaceuticals, Inc.
    Methocarbamol Tablet [Camber Pharmaceuticals, Inc.]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • American Health Packaging
    Methocarbamol Tablet [American Health Packaging]
  • Lake Erie Medical Dba Quality Care Products Llc
    Methocarbamol Tablet [Lake Erie Medical Dba Quality Care Products Llc]
  • American Health Packaging
    Methocarbamol Tablet [American Health Packaging]
  • Dispensing Solutions, Inc.
    Methocarbamol Tablet [Dispensing Solutions, Inc.]
  • Dispensing Solutions, Inc.
    Methocarbamol Tablet [Dispensing Solutions, Inc.]
  • Lake Erie Medical Dba Quality Care Products Llc
    Methocarbamol Tablet [Lake Erie Medical Dba Quality Care Products Llc]
  • A-s Medication Solutions Llc
    Methocarbamol Tablet [A-s Medication Solutions Llc]
  • Liberty Pharmaceuticals, Inc.
    Methocarbamol Tablet [Liberty Pharmaceuticals, Inc.]
  • Unit Dose Services
    Methocarbamol Tablet [Unit Dose Services]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • A-s Medication Solutions Llc
    Methocarbamol Tablet [A-s Medication Solutions Llc]
  • A-s Medication Solutions Llc
    Methocarbamol Tablet [A-s Medication Solutions Llc]
  • Clinical Solutions Wholesale
    Methocarbamol Tablet [Clinical Solutions Wholesale]
  • Clinical Solutions Wholesale
    Methocarbamol Tablet [Clinical Solutions Wholesale]
  • Pd-rx Pharmaceuticals, Inc.
    Methocarbamol Tablet [Pd-rx Pharmaceuticals, Inc.]
  • Sandoz Inc
    Methocarbamol Tablet [Sandoz Inc]
  • Virtus Pharmaceuticals
    Methocarbamol Tablet, Film Coated [Virtus Pharmaceuticals]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • Mckesson Packaging Services A Business Unit Of Mckesson Corporation
    Methocarbamol Tablet [Mckesson Packaging Services A Business Unit Of Mckesson Corporation]
  • Kaiser Foundation Hospitals
    Methocarbamol Tablet [Kaiser Foundation Hospitals]
  • Direct Rx
    Methocarbamol Tablet [Direct Rx]
  • Blenheim Pharmacal, Inc.
    Methocarbamol Tablet [Blenheim Pharmacal, Inc.]
  • Aphena Pharma Solutions – Tennessee, Llc
    Methocarbamol Tablet [Aphena Pharma Solutions – Tennessee, Llc]
  • Golden State Medical Supply, Inc.
    Methocarbamol Tablet, Film Coated [Golden State Medical Supply, Inc.]
  • Cardinal Health
    Methocarbamol Tablet [Cardinal Health]
  • Cardinal Health
    Methocarbamol Tablet [Cardinal Health]
  • Preferred Pharmaceuticals, Inc.
    Methocarbamol Tablet [Preferred Pharmaceuticals, Inc.]
  • Northwind Pharmaceuticals, Llc
    Methocarbamol Tablet [Northwind Pharmaceuticals, Llc]
  • West-ward Pharmaceutical Corp
    Methocarbamol Tablet [West-ward Pharmaceutical Corp]
  • State Of Florida Doh Central Pharmacy
    Methocarbamol Tablet [State Of Florida Doh Central Pharmacy]
  • State Of Florida Doh Central Pharmacy
    Methocarbamol Tablet [State Of Florida Doh Central Pharmacy]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]
  • Proficient Rx Lp
    Methocarbamol Tablet [Proficient Rx Lp]
  • Proficient Rx Lp
    Methocarbamol Tablet [Proficient Rx Lp]
  • Preferred Pharmaceuticals Inc.
    Methocarbamol Tablet [Preferred Pharmaceuticals Inc.]
  • Medsource Pharmaceuticals
    Methocarbamol Tablet [Medsource Pharmaceuticals]
  • Golden State Medical Supply, Inc.
    Methocarbamol Tablet [Golden State Medical Supply, Inc.]
  • Remedyrepack Inc.
    Methocarbamol Tablet [Remedyrepack Inc. ]

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