FDA records indicate that there are no current recalls for this drug.
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Questions & Answers
Side Effects & Adverse Reactions
Do not exceed recommended dosage.
Sympathomimetic amines should be used judiciously and sparingly in patients with hypertension, diabetes, ischemic heart disease, hyperthyroidism, increased intraocular pressure or prostatic hypertrophy (See CONTRAINDICATIONS). Sympathomimetic amines may produce CNS stimulation with convulsions or cardiovascular collapse with accompanying hypotension. The elderly (60 years and older) are more likely to exhibit adverse reactions. Antihistamines may cause excitability, especially in children. At doses higher than the recommended dose, nervousness, dizziness or sleeplessness may occur. Administration of dextromethorphan may be accompanied by histamine
release and should be used with caution in atopic children.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
For relief of coughs and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold.
History
There is currently no drug history available for this drug.
Other Information
CPM/PE/DM Syrup is a sugar-free, alcohol-free, grape flavored syrup for oral administration for adults and for pediatric patients 2 years and older.
Each teaspoonful (5 mL) contains:
Chlorpheniramine maleate ………………. 4.0 mg
Phenylephrine hydrochloride ……………. 12.5 mg
Dextromethorphan hydrobromide ……….. 15.0 mg
Inactive ingredients: Citric acid, D&C Red No. 33, FD&C Blue No. 1, flavor, glycerin, purified water, sodium benzoate, sodium saccharin, and sorbitol. May contain sodium citrate.
Chlorpheniramine maleate is an antihistamine with the chemical name: 2-Pyridinepropanamine, y -(4-chlorophenyl)-N, N-dimethyl-, (Z)-2-butenedioate (1:1). Its chemical structure is as follows:
Phenylephrine hydrochloride is a mydriatic and a decongestant with the chemical name: (-)-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride. Its chemical structure is as follows:
Dextromethorphan hydrobromide is an antitussive with the chemical name 3-Methoxy-17-methyl-9α, 13α, 14α - morphinan hydrobromide monohydrate. Its structure is as follows:
Sources
Sildec Pe Dm Syrup Manufacturers
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Rebel Distributors Corp
Sildec Pe Dm Syrup | Rebel Distributors Corp
CHLORPHENIRAMINE / PHENYLEPHRINE/ DEXTROMETHORPHAN Syrup (CPM/PE/DM Syrup) Adults and Children 12 years of age and older: 1 teaspoonful (5 mL) every 4 to 6 hours, not to exceed 6 teaspoonfuls in 24 hours. Children 6 to under 12 years of age: 1/2 teaspoonful (2.5 mL) every 4 to 6 hours, not to exceed 3 teaspoonfuls in 24 hours. Children 2 to under 6 years of age: 1/4 teaspoonful (1.25 mL) every 4 to 6 hours, not to exceed 1.5 teaspoonfuls in 24 hours. Not recommended for use in children under 2 years of age.
In mild cases or in particularly sensitive patients, less frequent or reduced doses may be appropriate and adequate.
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