Tranquived
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Questions & Answers
Side Effects & Adverse Reactions
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Do not use in Cervidae less than 15 days before or during the hunting season.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
Xylazine should be used in horses and Cervidae (Fallow Deer, Mule Deer, Sika Deer, White-Tailed Deer and Elk) when it is desirable to produce a state of sedation accompanied by a shorter period of analgesia.
Xylazine has been used successfully as follows:
- Diagnostic procedures ---- oral and ophthalmic examinations, abdominal palpation, rectal palpation, vaginal examination, catheterization of the bladder and radiographic examinations.
- Orthopedic procedures, such as application of casting materials and splints.
- Dental procedures.
- Minor surgical procedures of short duration such as debridement, removal of cutaneous neoplasms and suturing of lacerations.
- To calm and facilitate handling of fractious animals.
- Major surgical procedures:
- When used as a preanesthetic to general anesthesia.
- When used in conjunction with local anesthetics.
Xylazine may be used for the following:
- To calm and facilitate handling of fractious animals.
- Diagnostic procedures.
- Minor surgical procedures.
- Therapeutic medication for sedation and relief of pain following injury or surgery.
- As a preanesthetic to local anesthesia. TranquiVed at the recommended dosages can be used in conjunction with local anesthetics, such as procaine or lidocaine.
History
There is currently no drug history available for this drug.
Other Information
TranquiVed is supplied in 50 mL multiple-dose vials as a sterile solution.
Xylazine hydrochloride equivalent to 100 mg of base activity, methylparaben 0.9 mg, propylparaben 0.1 mg, sodium citrate dihydrate 5.0 mg and water for injection. pH adjusted with citric acid and sodium citrate.
Protect from heat. Do not store over 30° C (86° F).
Sources
Tranquived Manufacturers
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Vedco, Inc.
![Tranquived (Xylazine) Injection [Vedco, Inc.]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Tranquived | Vedco, Inc.
1. Dosage HorsesIntravenous --- 0.5 mL/100 lb body weight (0.5 mg/lb or 1.1 mg/kg).
Intramuscular --- 1.0 mL/100 lb body weight (1 mg/lb or 2.2 mg/kg).
CervidaeAdminister intramuscularly, by either hand syringe or syringe dart, in the heavy muscles of the croup or shoulder.
Fallow Deer (Dama dama) --- 2.0 to 4.0 mL/100 lbs body weight (2.0 to 4.0 mg/lb or 4.4 to 8.8 mg/kg).
Mule Deer (Odocoileus hemionus) --- 1.0 to 2.0 mL/100 lbs body weight (1.0 to 2.0 mg/lb or 2.2 to 4.4 mg/kg).
White-Tailed Deer (Odocoileus virginianus) --- 1.0 to 2.0 mL/100 lbs body weight (1.0 to 2.0 mg/lb or 2.2 to 4.4 mg/kg).
Elk (Cervus canadensis) --- 0.25 to 0.5 mL/100 lbs body weight (0.25 to 0.5 mg/lb or 0.55 to 1.1 mg/kg).
Following injection of xylazine, the animal should be allowed to rest quietly until the full effect has been reached.
These dosages produce sedation which is usually maintained for 1 to 2 hours, and analgesia which lasts for 15 to 30 minutes.
2. Preanesthetic to Local AnesthesiaXylazine at the recommended dosages can be used in conjunction with local anesthetics, such as procaine or lidocaine.
3. Preanesthetic to General AnesthesiaXylazine at the recommended dosage rates produces an additive effect to central nervous system depressants such as pentobarbital sodium, thiopental sodium and thiamylal sodium. Therefore, the dosage of such compounds should be reduced and administered to the desired effect. In general, only 1/3 to 1/2 of the calculated dosage of the barbiturates will be needed to produce a surgical plane of anesthesia. Post-anesthetic or emergence excitement has not been observed in animals preanesthetized with xylazine.
Xylazine has been used successfully as a preanesthetic agent for pentobarbital sodium, thiopental sodium, thiamylal sodium, nitrous oxide, ether, halothane, glyceryl guaiacolate and methoxyflurane anesthesia.
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