Supplementation of the diet with vitamins A, D, and C. TRI-VIT with FLUORIDE 0.5 mg drops also provide fluoride for caries prophylaxis. TRI-VIT with FLUORIDE 0.5 mg (vitamins A, D, C and fluoride) drops provide fluoride in drop form for children ages 3 to 6 years in areas where the drinking water contains less than 0.3 ppm of fluoride and for children 6 years of age and older in areas where the drinking water contains 0.3 through 0.6 ppm of fluoride.2 Each 1 mL supplies sodium fluoride (0.5 mg fluoride) plus three basic vitamins. TRI-VIT with FLUORIDE 0.5 mg drops supply significant amounts of vitamins A, D, and C to supplement the diet, and to help assure that nutritional deficiencies of these vitamins will not develop. Thus, in a single easy-to-use preparation, infants and children obtain three essential vitamins plus fluoride. A comprehensive 5 1/2 year series of studies of the effectiveness of vitamin-fluoride products in caries protection has been published.3-6 Children in this continuing study lived in an area where the water supply contained only 0.05 ppm fluoride. The subjects were divided into two groups, one which used only non-fluoridated vitamin products and other vitamin-fluoride products. The three-year interim report showed 63% fewer carious surfaces in primary teeth and 43% fewer carious surfaces in permanent teeth of the children taking vitamin-fluoride products.3 After four years the studies continued to support the effectiveness of vitamin-fluoride products, showing a reduction in carious surfaces of 68% in primary teeth and 46% in permanent teeth.4 Results at the end of 5 1/2 years further confirmed the previous findings and indicated that significant reductions in dental caries are apparent with the continued use of vitamin-fluoride products.5