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Uses
Cattle - Single-Dose Therapy: Baytril® 100 is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in beef and non-lactating dairy cattle; and for the control of BRD in beef and non-lactating dairy cattle at high risk of developing BRD associated with M. haemolytica, P. multocida, H. somni and M. bovis.
Cattle - Multiple-Day Therapy: Baytril® 100 is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni in beef and non-lactating dairy cattle.
Swine: Baytril® 100 is indicated for the treatment and control of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, Streptococcus suis, Bordetella bronchiseptica and Mycoplasma hyopneumoniae. Baytril® 100 is indicated for the control of colibacillosis in groups or pens of weaned pigs where colibacillosis associated with Escherichia coli has been diagnosed.
History
There is currently no drug history available for this drug.
Other Information
Baytril® 100 is a sterile, ready-to-use injectable antimicrobial solution that contains enrofloxacin, a broad-spectrum fluoroquinolone antimicrobial agent.
Each mL of Baytril® 100 contains 100 mg of enrofloxacin. Excipients are L-arginine base 200 mg, n-butyl alcohol 30 mg, benzyl alcohol (as a preservative) 20 mg and water for injection q.s.
1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid.
Sources
Veil Mineral Primer Spf 15 Manufacturers
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Kingdom Animalia, Llc, Dba Hourglass Cosmetics
Veil Mineral Primer Spf 15 | Bayer Healthcare Llc Animal Health Division
Baytril® 100 provides flexible dosages and durations of therapy.
Baytril® 100 may be administered as a single dose for one day for treatment and control of BRD (cattle), for treatment and control of SRD or for control of colibacillosis (swine), or for multiple days for BRD treatment (cattle). Selection of the appropriate dose and duration of therapy for BRD treatment in cattle should be based on an assessment of the severity of the disease, pathogen susceptibility and clinical response.
500 mL--Do not enter the vial with a needle more than 30 times or enter the vial with a dosage deliver device more than 4 times. Any product remaining after these maximum number of entries should be discarded.
Cattle:
Single-Dose Therapy (BRD Treatment): Administer, by subcutaneous injection, a single dose of 7.5-12.5 mg/kg of body weight (3.4-5.7 mL/100 lb).
Multiple-Day Therapy (BRD Treatment): Administer daily, a subcutaneous dose of 2.5-5 mg/kg of body weight (1.1-2.3 mL/100 lb). Treatment should be repeated at 24-hour intervals for three days. Additional treatments may be given on Days 4 and 5 to animals that have shown clinical improvement but not total recovery.
Single-Dose Therapy (BRD Control): Administer, by a subcutaneous injection, a single dose of 7.5 mg/kg of body weight (3.4 mL/100 lb). Examples of conditions that may contribute to calves being at high risk of developing BRD include, but are not limited to, the following:
• Transportation with animals from two or more farm origins. • An extended transport time with few to no rest stops. • An environmental temperature change of ≥30°F during transportation. • A ≥30°F range in temperature fluctuation within a 24-hour period. • Exposure to wet or cold weather conditions. • Excessive shrink (more than would be expected with a normal load of cattle). • Stressful arrival processing procedures (e.g., castration or dehorning). • Exposure within the prior 72 hours to animals showing clinical signs of BRD.Administered dose volume should not exceed 20 mL per injection site.
Table 1 – Baytril® 100 Dose and Treatment Schedule for Cattle* * Dose volumes have been rounded to the nearest 0.5 mL within the dose range.Weight
(lb)Treatment
Control
Single-Dose Therapy
7.5 - 12.5 mg/kg
Dose Volume (mL)Multiple-Day Therapy
2.5 - 5.0 mg/kg
Dose Volume (mL)Single-Dose Therapy
7.5 mg/kg
Dose Volume (mL)100
3.5 - 5.5
1.5 - 2.0
3.5
200
7.0 - 11.0
2.5 - 4.5
7.0
300
10.5 - 17.0
3.5 - 6.5
10.5
400
14.0 - 22.5
4.5 - 9.0
14.0
500
17.0 - 28.5
5.5 - 11.5
17.0
600
20.5 - 34.0
7.0 - 13.5
20.5
700
24.0 - 39.5
8.0 - 16.0
24.0
800
27.5 - 45.5
9.0 - 18.0
27.5
900
31.0 - 51.0
10.0 - 20.5
31.0
1000
34.0 - 57.0
11.0 - 23.0
34.0
1100
37.5 - 62.5
12.5 - 25.0
37.5
Swine:
Administer, either by intramuscular or subcutaneous (behind the ear) injection, a single dose of 7.5 mg/kg of body weight (3.4 mL/100 lb). Administered dose volume should not exceed 5 mL per injection site.
For the control of colibacillosis, administration should be initiated within the first 60 days post-weaning when clinical signs are present in at least 2% of the animals in the group. If no improvement is noted within 48 hours, the diagnosis should be reevaluated.
Table 2 – Baytril® 100 Dose Schedule for SwineWeight (lb)
Dose Volume (mL)
15
0.5
30
1.0
50
1.7
100
3.4
150
5.1
200
6.8
250
8.5
Dilution of Baytril® 100: Baytril® 100 may be diluted with sterile water prior to injection. The diluted product should be used within 24 hours. Store diluted solution in amber glass bottles between 4-40°C (36-104°F).
Table 3 – Dilution Schedule* * For 1 mL dose volume from diluted solutionSwine Weight
mL of Baytril® 100
mL of sterile water
Number of doses
10 lb
34 mL
66 mL
100
15 lb
51 mL
49 mL
100
20 lb
68 mL
32 mL
100
25 lb
85 mL
15 mL
100
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