Walgreens Sterile Original Eye Drops
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Questions & Answers
Side Effects & Adverse Reactions
For use in animals only. Do not use in horses intended for human consumption. Not for human use. Keep out of the reach of children.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
There are currently no FDA safety alerts available for this drug.
Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
Marquis (ponazuril) is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona.
History
There is currently no drug history available for this drug.
Other Information
Marquis® (15% w/w ponazuril) Antiprotozoal Oral Paste is supplied in a ready-to-use syringe containing 127 grams of paste. Each gram of paste contains 150 mg of ponazuril (15% w/w). Marquis (ponazuril) is designed to be delivered as an orally administered paste.
Each syringe barrel of Marquis (ponazuril) contains enough paste to treat one (1) 1,200 lb (544 kg) horse for seven (7) days, at a dose rate of 5 mg/kg (2.27 mg/lb) body weight. The plunger contains a dosage ring calibrated for a dose rate of 5 mg/kg (2.27 mg/lb) body weight and marked for horse weight from 600 to 1,200 lbs (272 to 544 kg). The syringe barrel is packaged with a reusable plunger. This package provides sufficient paste to treat one 1,200 lb (544 kg) horse for seven days at a rate of 5 mg/kg (2.27 mg/lb) body weight.
Ponazuril is an anticoccidial (antiprotozoal) compound with activity against several genera of the phylum Apicomplexa.
Sources
Walgreens Sterile Original Eye Drops Manufacturers
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Walgreens Company
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Walgreens Sterile Original Eye Drops | Bayer Healthcare, Llc
Marquis (15% w/w ponazuril) is to be used at a dose of 5 mg/kg (2.27 mg/lb) body weight once daily for a period of 28 days.
ADMINISTRATION:
Paste syringe assembly:
Before administration, the syringe barrel and plunger require assembly. Ensure plunger is clean and dry.
Step 1. End cap must be on syringe barrel when inserting plunger.
Step 2. Carefully insert reusable plunger into base of syringe barrel until it snaps into place, then remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel.
Step 3. Return end cap to tip of paste syringe.
Administering Marquis (ponazuril) to the horse:
NOTE: The paste syringe is a multi-dose package. Ensure that the correct dose is administered with each use.
Step 1. Remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. Return end cap to tip of paste syringe.
Step 2. Determine weight of horse and insure the horse’s mouth contains no feed.
Step 3. To measure dose, dosage ring collar and barrel collar should be flush. Hold plunger and rotate dosage ring with the other hand to the weight of the horse.
Step 4. Remove end cap from tip of syringe barrel.
Step 5. The selected dose of paste should be deposited onto the back and top of the horse’s tongue. Introduce tip of paste syringe into the side of the horse’s mouth at the space between the front (incisor) and back (molar) teeth. Deposit paste on the horse’s tongue by depressing the plunger of the syringe as far as the dose ring permits. Remove tip of syringe from horse’s mouth.
Step 6. To aid swallowing of paste, immediately raise horse’s head for a few seconds after dosing.
Step 7. Clean the tip of the syringe with a clean disposable towel and return end cap to tip of syringe barrel.
Step 8. For the next daily dose, repeat steps 1-7.
NOTE: At the end of the prescribed treatment period, partially used syringes should be discarded.
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