Bayer Healthcare Llc Animal Health Division

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Bayer Healthcare Llc Animal Health Division Drugs

Ciprofloxacin

Ciprofloxacin

Droncit® Feline Cestocide Tablets may be administered directly per os or crumbled and mixed with the feed. The recommended dosage of praziquantel varies according to body weight. Smaller animals require a relatively larger dosage because of their higher metabolic rate. The optimum dose for each individual animal will be achieved by utilizing the following dosage schedule:
* Not intended for use in kittens less than 6 weeks of age.
Cats and Kittens*

4 pounds and under

½ tablet

5-11 pounds

1 tablet

Over 11 pounds

1 ½ tablets
Butorphanol Tartrate

Butorphanol Tartrate

The recommended dosage in the horse is 0.1 mg of butorphanol per kilogram of body weight, (0.05 mg/lb) by intravenous injection. This is equivalent to 5 mL of Butorphanol Tartrate Injection for each 1000 lbs body weight. The dose may be repeated within 3 to 4 hours but treatment should not exceed 48 hours. Pre-clinical model studies and clinical field trials in horses demonstrate that the analgesic effects of Butorphanol Tartrate Injection are seen within 15 minutes following injection and persist for about 4 hours.
Drontal Plus

Drontal Plus

The presence of parasites should be confirmed by laboratory fecal examination. Weigh the animal before treatment. Administer the proper dosage as specified in the following table as a single oral treatment.
DOSAGE CHARTS * NOT FOR USE IN PUPPIES LESS THAN 3 WEEKS OF AGE OR DOGS WEIGHING LESS THAN 2 LBS.
Drontal® Plus

Tablets

for Puppies and

Small Dogs*

(2 - 25 lbs.)

Drontal® Plus

Tablets

for Medium

Sized Dogs

(26 - 60 lbs.)

Drontal® Plus

Tablets

for Large Dogs

(45 lbs.

and greater)

Body Wt. (lbs.)

No. of Tablets

Body Wt. (lbs.)

No. of Tablets

Body Wt. (lbs.)

No. of Tablets

2 – 4

5 – 7

8 – 12

13 – 18

19 – 25

0.5

1.0

1.5

2.0

2.5

26 – 30

31 – 44

45 – 60

1.0

1.5

2.0

45 – 60

61 – 90

91 – 120

1.0

1.5

2.0
Droncit

Droncit

Droncit (praziquantel) Injectable Cestocide may be administered by either the subcutaneous or intramuscular route to dogs and cats. The recommended dosage of praziquantel varies according to body weight. Smaller animals require a relatively larger dosage. The optimum dosage for each individual animal will be achieved by utilizing the following dosage schedule.

DOGS AND PUPPIES†

Dogs:

5 lbs. and under      0.3 mL

6-10 lbs.                  0.5 mL

11-25 lbs.                1.0 mL

over 25 lbs.             0.2 mL /5 lbs.                                body weight to a                                 maximum of 3 mL

† Not intended for use in puppies less than four (4) weeks of age.

CATS AND KITTENS††

Cats:

Under 5 lbs.            0.2 mL

5-10 lbs.                  0.4 mL

11 lbs. and over      0.6 mL maximum

†† Not intended for use in kittens less than six (6) weeks of age.

FASTING:

The recommended dosage of praziquantel is not affected by the presence or absence of food in the gastrointestinal tract, therefore, FASTING IS NEITHER NECESSARY NOR RECOMMENDED.

ADMINISTRATION:

Droncit (praziquantel) Injectable Cestocide may be administered by either the subcutaneous or intramuscular route to dogs and cats. The intramuscular route may be preferred in dogs due to a brief period of pain that occasionally follows subcutaneous administration. Anaphylactoid reactions were not observed in clinical trials. However, as with any drug an anaphylactoid reaction can occur with this product and should be treated symptomatically if it occurs.

RETREATMENT:

For those animals living where reinfections are likely to occur, clients should be instructed in the steps to optimize prevention, otherwise, retreatment may be necessary. This is true in cases of Dipylidium caninum where reinfection is almost certain to occur if fleas are not removed from the animal and its environment. In addition, for control of Echinococcus multilocularis, a program of regular treatment every 21 to 26 days may be indicated (see E. multilocularis section below).

ECHINOCOCCUS MULTILOCULARIS:

Echinococcus multilocularisis a tapeworm species ordinarily considered to be found in wild canids, including foxes, coyotes and wolves. The parasite has also been identified in domestic dogs and cats and potentially is a serious public health concern by involving humans as accidental intermediate hosts.

The life cycle of the parasite is based on a predator-prey relationship, as depicted above.

The adult tapeworm is small (1-4mm) and resides in the intestinal tract of the definitive host (wild or domestic canids). Eggs from the adult tapeworm are shed in the feces of the infected canid. Rodents such as mice and voles serve as the intermediate host for E. multilocularis. Eggs ingested by rodents develop in the liver, lungs and other organs to form multilocular cysts. The life cycle is completed after a canid consumes a rodent infected with cysts. After ingestion of the infected rodent, larvae within the cyst develop to adult tapeworms in the intestinal tract of the canid. Eggs may begin to be passed in the feces of the canid approximately 28 days later.

This parasite poses a serious public health problem because of the possibility for human involvement in the life cycle. If eggs shed by an infected canid are accidentally ingested, a highly pathogenic condition (Alveolar Hydatid Disease) results from development of the cyst stage in humans.

The original geographic distribution of E. multilocularis was primarily confined to northern areas of North America. Current evidence indicates migration of the parasite well into the continental United States.2,3

Domestic dogs living in E. multilocularis endemic areas that roam freely with the opportunity to catch wild rodents are at risk for infection. Pet owners should be advised on how to minimize this risk. Proper restraint of roaming dogs should be encouraged, along with regular treatment with Droncit Injectable solution, following the dosing schedule aforementioned and precautions indicated below.

Additional information on the life cycle and epidemiology of this parasite is available in veterinary parasitology texts.4,5

Diagnosis:

Diagnosis of E. multilocularis in canids is difficult. The adult tapeworm produces no clinical signs of infection. Tapeworm segments (proglottids) are usually not observed in the feces. E. multilocularis eggs, observed using microscopic fecal examination procedures, are similar in appearance to the common taeniid species of canids such as Taenia pisiformis.

Assistance in the diagnosis of E. multilocularis may be available from a state veterinary diagnostic laboratory. Additional information regarding areas where E. multilocularis is suspected or has been confirmed may be obtained from area veterinary schools or the Centers for Disease Control in Atlanta, GA.

Treatment:

Dogs infected with E. multilocularis should be treated to prevent exposure of humans to infective eggs and to reduce perpetuation of the parasite's life cycle.

The dosage of Droncit Injectable solution for removal of E. multilocularis is the same as that indicated for the removal of the other tapeworm species listed on the label. Laboratory efficacy studies have demonstrated the recommended dosage is 100% efficacious for removal of this tapeworm.

Under condition of continual exposure to wild rodents, retreatment of the dog at 21-26 day intervals is recommended to prevent the shedding of infectious eggs.
A3802-18 Continuous Epi...

A3802-18 Continuous Epidural 18g Crawford18g Hustead

Droncit® (praziquantel) Canine Cestocide Tablets may be administered directly per os or crumbled and mixed with the feed. The recommended dosage of praziquantel varies according to body weight. Smaller animals require a relatively larger dosage because of their higher metabolic rate. The optimum dose for each individual animal will be achieved by utilizing the following dosage schedule:

* Not intended for use in puppies less than 4 weeks of age.
Dogs and Puppies*

              5 lbs. and under

   ½ tablet

         6-10 lbs.

    1 tablet

       11-15 lbs.

1 ½ tablets

       16-30 lbs.

    2 tablets

       31-45 lbs.

    3 tablets

       46-60 lbs.

    4 tablets

   Over 60 lbs.

    5 tablets max
Catosal

Catosal

Give by subcutaneous, intramuscular or intravenous injection according to the following table:
Repeat daily as needed. Cattle 1 - 2 mL per 100 lbs body weight Calves 2 - 4 mL per 100 lbs body weight Horses 1 - 2 mL per 100 lbs body weight Swine 2 - 5 mL per 100 lbs body weight Piglets 1 - 2.5 mL per animal Poultry 1 - 3 mL per Liter drinking water
Drontal

Drontal

To assure proper dosage, weigh the cat prior to treatment. Select the number of whole or partial tablets needed for the cat from the following table.
* NOT FOR USE IN KITTENS LESS THAN TWO MONTHS OF AGE OR WEIGHING LESS THAN 2 LBS.
Body Weight* (lbs.)

Number of Tablets

2 – 3

1/2

4 – 8

1

9 – 12

1 1/2

13 – 16

2

Drontal® Tablets may be given directly by mouth or offered in a small amount of food. Do not withhold food from the cat prior to or after treatment.
Leader Milk Of Magnesia...

Leader Milk Of Magnesia Saline Laxative

The recommended minimum dose is 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin, once a month, by topical administration.

Do not apply to irritated skin.

1. Remove one dose applicator tube (tube) from the package. As specified in the following table, administer the entire contents of the Advantage Multi for Cats tube that correctly corresponds with the body weight of the cat.
* Cats over 18 lbs. should be treated with the appropriate combination of Advantage Multi for Cats tubes.
Cat (lbs.)

Advantage Multi for Cats

Volume

(mL)

Imidacloprid

(mg)

Moxidectin

(mg)

2–5

Advantage Multi 5

0.23

23

2.3

5.1–9

Advantage Multi 9

0.4

40

4

9.1–18*

Advantage Multi 18

0.8

80

8

2. While holding the tube in an upright position, remove the cap from the tube.

3. Turn the cap over and push the other end of cap onto the tip of the tube.

4. Twist the cap to break the seal and then remove cap from the tube.

5. Part the hair on the back of the cat’s neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube.

Do not get this product in the cat’s mouth or eyes or allow the cat to lick the application site for 30 minutes. Treatment at the base of the head will minimize the opportunity for ingestion by grooming. In households with multiple pets, keep animals separated to prevent licking of the application site.

Stiff, matted hair or a damp, oily appearance of the hair may be observed at the application site on some cats. This is temporary and does not affect the safety and effectiveness of the product.

Heartworm Prevention: For prevention of heartworm disease, Advantage Multi for Cats should be administered at one-month intervals. Advantage Multi for Cats may be administered year-around or at a minimum should start one month before the first expected exposure to mosquitoes and should continue at monthly intervals until one month after the last exposure to mosquitoes. If a dose is missed and a 30-day interval between doses is exceeded, administer Advantage Multi for Cats immediately and resume the monthly dosing schedule. When replacing another heartworm preventative product in a heartworm prevention program, the first treatment with Advantage Multi for Cats should be given within one month of the last dose of the former medication. At the discretion of the veterinarian, cats older than 6 months of age may be tested to determine the presence of existing heartworm infection before treatment with Advantage Multi for Cats (See ADVERSE REACTIONS – Post-Approval Experience).

Flea Treatment: For the treatment of flea infestations, Advantage Multi for Cats should be administered at one-month intervals. If the cat is already infested with fleas when the first dose of Advantage Multi for Cats is administered, adult fleas on the cat will be killed. However, re-infestation from the emergence of pre-existing pupae in the environment may continue to occur for six weeks or longer after treatment is initiated. Cats treated with imidacloprid, including those with pre-existing flea allergy dermatitis have shown clinical improvement as a direct result of elimination of fleas from the cat.

Ear Mite Treatment: For the treatment of ear mites (Otodectes cynotis), Advantage Multi for Cats should be administered once as a single topical dose. Monthly use of Advantage Multi for Cats will control any subsequent ear mite infestations.

Intestinal Nematode Treatment: For the treatment and control of intestinal hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults and fourth stage larvae) and roundworm infections caused by Toxocara cati (adults and fourth stage larvae), Advantage Multi for Cats should be administered once as a single topical dose.

For ferrets:

The recommended minimum dose for a ferret is 9 mg/lb (20 mg/kg) imidacloprid and 0.9 mg/lb (2 mg/kg) moxidectin, once a month, by topical administration.

Ferret (lbs.)

Advantage Multi for Cats

Volume (mL)

Imidacloprid (mg)

Moxidectin (mg)

2.0-4.4

Advantage Multi 9

0.4

40

4

Only the 0.4 mL applicator tube volume (Advantage Multi 9) should be used on ferrets.

Do not apply to irritated skin.

1. Remove one dose applicator tube (tube) from the package. Administer the entire contents of the Advantage Multi for Cats tube (0.4 mL).

2. While holding the tube in an upright position, remove the cap from the tube.

3. Turn the cap over and push the other end of cap onto the tip of the tube.

4. Twist the cap to break the seal and then remove cap form the tube.

5. Part the hair on the back of the ferret’s neck at the case of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube.

Do not get this product in the ferret’s mouth or eyes or allow the ferret to lick the application site for 30 minutes. Treatment at the base of the head will minimize the opportunity for ingestion by grooming. In households with multiple pets, keep animals separated to prevent licking of the application site.

Stiff, matted hair or a damp, oily appearance of the hair may be observed at the application site on some ferrets. This is temporary and does not affect the safety or effectiveness of the product.

Heartworm Prevention: For prevention of heartworm disease, Advantage Multi for Cats should be administered at one-month intervals. Advantage Multi for Cats may be administered year-round or at a minimum should start one month before the first expected exposure to mosquitoes and should continue at monthly intervals until one month after the last exposure to mosquitoes. If a dose is missed and a 30-day interval between doses is exceeded, administer Advantage Multi for Cats immediately and resume the monthly dosing schedule.

Flea Treatment: For the treatment of flea infestations on ferrets, Advantage Multi for Cats should be administered at one-month intervals. If the ferret is already infested with fleas when the first dose of Advantage Multi for Cats is administered, adult fleas on the ferret will be killed. However, re-infestation from the emergence of pre-existing pupae in the environment may continue to occur for six weeks or longer after treatment is initiated.
Veraflox

Veraflox

Shake well before use. To ensure a correct dosage, body weight should be determined as accurately as possible. The dose of VERAFLOX is 7.5 mg/kg (3.4 mg/lb) body weight once daily for 7 consecutive days. Use the syringe provided to ensure accuracy of dosing to the nearest 0.1 mL. Rinse syringe between doses.

A sample of the lesion should be obtained for culture and susceptibility testing prior to beginning antibacterial therapy. Once results become available, continue with appropriate therapy. If acceptable response to treatment is not observed, or if no improvement is seen within 3 to 4 days, then the diagnosis should be re-evaluated and appropriate alternative therapy considered.
Legend

Legend

4 mL (40 mg) injected intravenously. Treatment may be repeated at weekly intervals for a total of three treatments.

Use aseptic technique and inject slowly into the jugular vein.

Horses should be given stall rest after treatment before gradually resuming normal activity.

Discard any unused portion of the drug and empty vial after opening.
Legend

Legend

Intravenously-4 mL (40 mg), Intra-articular- 2 mL (20 mg) in the carpus or fetlock. Treatment may be repeated at weekly intervals for a total of three treatments.

Strict aseptic technique should be observed when administering by intra-articular injection. As with any intra-articular procedure, proper injection site disinfection and animal restraint are important. Excess joint fluid should be aseptically removed prior to injection. Care should be taken to avoid scratching the cartilage surface with the tip of the injection needle. Diffuse swelling lasting 24 to 48 hours may result from movement of the needle while in the joint space.

For intravenous administration, use aseptic technique and inject slowly into the jugular vein.

Horses should be given stall rest after treatment before gradually resuming normal activity.

Discard any unused portion of the drug and the empty vial after opening.
Legend

Legend

4 mL (40 mg) injected intravenously. Treatment may be repeated at weekly intervals for a total of three treatments.

Use aseptic technique and inject slowly into the jugular vein.

Horses should be given stall rest after treatment before gradually resuming normal activity.
Pain And Fever

Pain And Fever

The recommended minimum dose is 4.5 mg/lb (10 mg/kg) imidacloprid and 1.1 mg/lb (2.5 mg/kg) moxidectin, once a month, by topical administration.

Do not apply to irritated skin.

1. Remove one dose applicator tube (tube) from the package. As specified in the following table, administer the entire contents of the Advantage Multi for Dogs tube that correctly corresponds with the body weight of the dog.
* Dogs over 110 lbs. should be treated with the appropriate combination of Advantage Multi for Dogs tubes.
Dog (lbs.)

Advantage Multi For Dogs

Volume

(mL)

Imidacloprid

(mg)

Moxidectin

(mg)

3–9

Advantage Multi 9

0.4

40

10

9.1–20

Advantage Multi 20

1.0

100

25

20.1–55

Advantage Multi 55

2.5

250

62.5

55.1–88

Advantage Multi 88

4.0

400

100

88.1–110*

Advantage Multi 110

5.0

500

125

2. While holding the tube in an upright position, remove the cap from the tube.

3. Turn the cap over and push the other end of cap onto the tip of the tube.

4. Twist the cap to break the seal and then remove cap from the tube.

5. The dog should be standing for application. Part the hair on the back of the dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of the dog.

Do not let this product get in your dog’s mouth or eyes. Do not allow the dog to lick any of the application sites for 30 minutes. In households with multiple pets, keep each treated dog separated from other treated dogs and other pets for 30 minutes after application to prevent licking the application sites.(See WARNINGS.)

Stiff hair, a damp appearance of the hair, pink skin, or a slight powdery residue may be observed at the application site on some animals. This is temporary and does not affect the safety and effectiveness of the product.

Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi for Dogs in the prevention of heartworm disease.Shampooing or water immersion 4 days after treatment will not reduce the effectiveness of Advantage Multi for Dogs in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas.

Heartworm Prevention: For prevention of heartworm disease, Advantage Multi for Dogs should be administered at one-month intervals. Advantage Multi for Dogs may be administered year-round or at a minimum should start one month before the first expected exposure to mosquitoes and should continue at monthly intervals until one month after the last exposure to mosquitoes. If a dose is missed and a 30-day interval between doses is exceeded, administer Advantage Multi for Dogs immediately and resume the monthly dosing schedule. When replacing another heartworm preventative product in a heartworm prevention program, the first treatment with Advantage Multi for Dogs should be given within one month of the last dose of the former medication.

Treatment of Circulating Microfilariae: For the treatment of circulating D. immitis microfilariae in heartworm-positive dogs, Advantage Multi for Dogs should be administered at one-month intervals. Treatment with an approved adulticide therapy is recommended because Advantage Multi for Dogs is not effective for the treatment of adult D. immitis.(See PRECAUTIONS.)

Flea Treatment: For the treatment of flea infestations, Advantage Multi for Dogs should be administered at one-month intervals. If the dog is already infested with fleas when the first dose of Advantage Multi for Dogs is administered, adult fleas on the dog will be killed. However, reinfestation from the emergence of preexisting pupae in the environment may continue to occur for six weeks or longer after treatment is initiated. Dogs treated with imidacloprid, including those with pre-existing flea allergy dermatitis have shown clinical improvement as a direct result of elimination of fleas from the dog.

Treatment and Control of Intestinal Nematode Infections: For the treatment and control of intestinal hookworm infections caused by Ancylostoma caninum and Uncinaria stenocephala (adults, immature adults and fourth stage larvae) and roundworm infections caused by Toxocara canis (adults and fourth stage larvae), and Toxascaris leonina (adults), and whipworm infections caused by Trichuris vulpis (adults), Advantage Multi for Dogs should be administered once as a single topical dose.

Treatment and Control of Sarcoptic Mange: For the treatment and control of sarcoptic mange caused by Sarcoptes scabiei var. canis, Advantage Multi for Dogs should be administered as a single topical dose. A second monthly dose may be administered if necessary.
Drontal Plus Taste Tabs...

Drontal Plus Taste Tabs

The presence of parasites should be confirmed by laboratory fecal examination. Weigh the animal before treatment. Administer the proper dosage as specified in the following table as a single oral treatment.
DRONTAL® PLUS TASTE TABS® TABLETS DOSAGE CHARTS * NOT FOR USE IN PUPPIES LESS THAN 3 WEEKS OF AGE OR DOGS WEIGHING LESS THAN 2 LBS.
for Puppies and Small Dogs*

(2 - 25 lbs.)

for Medium Sized Dogs

(26 - 60 lbs.)

for Large Dogs

(45 lbs. and greater)

Body Wt.

(lbs.)

No. of

Tablets

Body Wt.

(lbs.)

No. of

Tablets

Body Wt.

(lbs.)

No. of

Tablets

2 – 4

0.5

26 – 30

1.0

45 – 60

1.0

5 – 7

1.0

31 – 44

1.5

61 – 90

1.5

8 – 12

1.5

45 – 60

2.0

91 – 120

2.0

13 – 18

2.0

19 – 25

2.5

Most dogs find Drontal® Plus Taste Tabs® Tablets palatable. The tablets may be offered to the dog by hand. Alternatively tablets may be given directly by mouth or offered in a small amount of food. Fasting is neither necessary nor recommended prior to or after treatment.
Veil Mineral Primer Spf...

Veil Mineral Primer Spf 15

Baytril® 100 provides flexible dosages and durations of therapy.

Baytril® 100 may be administered as a single dose for one day for treatment and control of BRD (cattle), for treatment and control of SRD or for control of colibacillosis (swine), or for multiple days for BRD treatment (cattle). Selection of the appropriate dose and duration of therapy for BRD treatment in cattle should be based on an assessment of the severity of the disease, pathogen susceptibility and clinical response.

500 mL--Do not enter the vial with a needle more than 30 times or enter the vial with a dosage deliver device more than 4 times. Any product remaining after these maximum number of entries should be discarded.

Cattle:

Single-Dose Therapy (BRD Treatment): Administer, by subcutaneous injection, a single dose of 7.5-12.5 mg/kg of body weight (3.4-5.7 mL/100 lb).

Multiple-Day Therapy (BRD Treatment): Administer daily, a subcutaneous dose of 2.5-5 mg/kg of body weight (1.1-2.3 mL/100 lb). Treatment should be repeated at 24-hour intervals for three days. Additional treatments may be given on Days 4 and 5 to animals that have shown clinical improvement but not total recovery.

Single-Dose Therapy (BRD Control): Administer, by a subcutaneous injection, a single dose of 7.5 mg/kg of body weight (3.4 mL/100 lb). Examples of conditions that may contribute to calves being at high risk of developing BRD include, but are not limited to, the following:
• Transportation with animals from two or more farm origins. • An extended transport time with few to no rest stops. • An environmental temperature change of ≥30°F during transportation. • A ≥30°F range in temperature fluctuation within a 24-hour period. • Exposure to wet or cold weather conditions. • Excessive shrink (more than would be expected with a normal load of cattle). • Stressful arrival processing procedures (e.g., castration or dehorning). • Exposure within the prior 72 hours to animals showing clinical signs of BRD.
Administered dose volume should not exceed 20 mL per injection site.
Table 1 – Baytril® 100 Dose and Treatment Schedule for Cattle* * Dose volumes have been rounded to the nearest 0.5 mL within the dose range.
Weight(lb)

Treatment

Control

Single-Dose Therapy7.5 - 12.5 mg/kgDose Volume (mL)

Multiple-Day Therapy2.5 - 5.0 mg/kgDose Volume (mL)

Single-Dose Therapy7.5 mg/kgDose Volume (mL)

100

3.5 - 5.5

1.5 - 2.0

3.5

200

7.0 - 11.0

2.5 - 4.5

7.0

300

10.5 - 17.0

3.5 - 6.5

10.5

400

14.0 - 22.5

4.5 - 9.0

14.0

500

17.0 - 28.5

5.5 - 11.5

17.0

600

20.5 - 34.0

7.0 - 13.5

20.5

700

24.0 - 39.5

8.0 - 16.0

24.0

800

27.5 - 45.5

9.0 - 18.0

27.5

900

31.0 - 51.0

10.0 - 20.5

31.0

1000

34.0 - 57.0

11.0 - 23.0

34.0

1100

37.5 - 62.5

12.5 - 25.0

37.5

Swine:

Administer, either by intramuscular or subcutaneous (behind the ear) injection, a single dose of 7.5 mg/kg of body weight (3.4 mL/100 lb). Administered dose volume should not exceed 5 mL per injection site.

For the control of colibacillosis, administration should be initiated within the first 60 days post-weaning when clinical signs are present in at least 2% of the animals in the group. If no improvement is noted within 48 hours, the diagnosis should be reevaluated.
Table 2 – Baytril® 100 Dose Schedule for Swine
Weight (lb)

Dose Volume (mL)

15

0.5

30

1.0

50

1.7

100

3.4

150

5.1

200

6.8

250

8.5

Dilution of Baytril® 100: Baytril® 100 may be diluted with sterile water prior to injection. The diluted product should be used within 24 hours. Store diluted solution in amber glass bottles between 4-40°C (36-104°F).
Table 3 – Dilution Schedule* * For 1 mL dose volume from diluted solution
Swine Weight

mL of Baytril® 100

mL of sterile water

Number of doses

10 lb

34 mL

66 mL

100

15 lb

51 mL

49 mL

100

20 lb

68 mL

32 mL

100

25 lb

85 mL

15 mL

100
Profender

Profender

The recommended minimum dose is 1.36 mg/lb (3 mg/kg) emodepside + 5.45 mg/lb (12 mg/kg) praziquantel as a single topical dose. A single treatment is effective and a second treatment should not be necessary. If re-infection occurs, the product can be re-applied after 30 days.

1. Select the package that correctly corresponds with the body weight of the cat. (See Table below.)

Cat

Weight*

Profender

Topical Solution

Volume

(mL)

Emodepside

(mg)

Praziquantel

(mg)

2.2-5.5 lbs.

Small

0.35

7.5

30.0

>5.5-11 lbs.

Medium

0.70

15.0

60.1

>11-17.6 lbs.

Large

1.12

24.0

96.1

* Cats over 17.6 lbs should be treated with the appropriate combination of tubes.

2. Remove one unit dose tube from the package.

3. While holding the tube in an upright position, remove the cap from the tube.

4. Turn the cap over and place the other end of cap onto the tip of the tube.

5. Twist the cap to break the seal and then remove cap from the tube.

6. Part the hair on the back of the cat’s neck at the base of the head, until the skin is visible.

7. To ensure the entire contents of the tube are administered, place the tip of the tube on the skin and squeeze the entire contents directly onto the skin. Lift tube away from the skin before releasing pressure on the tube.

Do not apply to broken skin or if hair coat is wet.

Do not get this product in the cat’s mouth or eyes or allow the cat to lick the application site for one hour. Oral exposure can cause salivation and vomiting. Treatment at the base of the head will minimize the opportunity for ingestion while grooming. In households with multiple pets, keep animals separated to prevent licking of the application site.

Stiff hair, a damp appearance of the hair, or a slight powdery residue may be observed at the treatment site. These effects are temporary and do not affect the safety or effectiveness of the product.
Expert Care Tapeworm De...

Expert Care Tapeworm Dewormer For Dogs

Tapeworm Dewormer (praziquantel) tablets may be given directly in the mouth or crumbled and mixed with the food. Administer to dogs and puppies* only as follows:

Body Weight (lbs)

No. of Tablets

5 lbs. and under

½ tablet

6-10 lbs.

1 tablet

11-15 lbs.

1 ½ tablets

16-30 lbs.

2 tablets

31-45 lbs.

3 tablets

46-60 lbs.

4 tablets

Over 60 lbs.

5 tablets maximum

*Not intended for use in puppies less than 4 weeks of age.

FASTING IS NEITHER NECESSARY NOR RECOMMENDED.
Expert Care Tapeworm De...

Expert Care Tapeworm Dewormer For Cats

Tapeworm Dewormer (praziquantel) tablets may be given directly in the mouth or crumbled and mixed with the food. Administer to cats and kittens* only as follows:

Body Weight (lbs)

No. of Tablets

4 pounds and under

½ tablet

5-11 pounds

1 tablet

Over 11 pounds

1½ tablets

*Not intended for use in kittens less than 6 weeks of age.

FASTING IS NEITHER NECESSARY NOR RECOMMENDED.
Baytril Otic

Baytril Otic

Shake well before each use.

Tilt head so that the affected ear is presented in an upward orientation. Administer a sufficient quantity of Baytril® Otic to coat the aural lesions and the external auditory canal. As a general guide, administer 5-10 drops per treatment in dogs weighing 35 lbs. or less and 10-15 drops per treatment in dogs weighing more than 35 lbs. Following treatment, gently massage the ear so as to ensure complete and uniform distribution of the medication throughout the external ear canal. Apply twice daily for a duration of up to 14 days.
Baytril

Baytril

Baytril Injectable Solution may be used as the initial dose at 2.5 mg/kg. It should be administered intramuscularly (IM) as a single dose, followed by initiation of Baytril Tablet therapy.

Baytril Injectable Solution may be administered as follows:
* The initial Baytril Injectable administration should be followed 12 hours later by initiation of Baytril Tablet therapy.

WeightofAnimal

Baytril

Injectable

Solution*

2.5 mg/kg

9.1 kg(20 lb)

1.00 mL

27.2 kg(60 lb)

3.00 mL

The lower limit of the dose range was based on efficacy studies in dogs where enrofloxacin was administered at 2.5 mg/kg twice daily. Target animal safety and toxicology studies were used to establish the upper limit of the dose range and treatment duration.
Baytril

Baytril

Dogs: Administer orally at a rate to provide 5-20 mg/kg (2.27 to 9.07 mg/lb) of body weight. Selection of a dose within the range should be based on clinical experience, the severity of disease, and susceptibility of the pathogen. Animals which receive doses in the upper-end of the dose range should be carefully monitored for clinical signs that may include inappetence, depression, and vomition.
All tablet sizes are double scored for accurate dosing.
Weight of Dog

Once Daily Dosing Chart

5.0 mg/kg

10.0 mg/kg

15.0 mg/kg

20.0 mg/kg

9.1 kg(20 lb)

2 x 22.7 mgtablets

1 x 22.7 mg plus1 x 68 mg tablets

1 x 136 mgtablet

1 x 136 mg plus2 x 22.7 mg tablets

27.2 kg(60 lb)

1 x 136 mgtablet

2 x 136 mgtablets

3 x 136 mgtablets

4 x 136 mgtablets

Cats: Administer orally at 5 mg/kg (2.27 mg/lb) of body weight. The dose for dogs and cats may be administered either as a single daily dose or divided into two (2) equal daily doses administered at twelve (12) hour intervals. The dose should be continued for at least 2-3 days beyond cessation of clinical signs, to a maximum of 30 days.
All tablet sizes are double scored for accurate dosing.
Weight of Cat

Once Daily Dosing Chart (5 mg/kg/day)

5 lb(2.27 kg)

1/2 x 22.7 mg tablet

10 lb(4.5 kg)

1 x 22.7 mg tablet

15 lb(6.8 kg)

1 and 1/2 x 22.7 mg tablets or1/2 x 68 mg tablet

Palatability: Most dogs will consume Baytril® Taste Tabs® Tablets willingly when offered by hand. Alternatively the tablet(s) may be offered in food or hand-administered (pilled) as with other oral tablet medications. In cats, Baytril® Taste Tabs® Tablets should be pilled. After administration, watch the animal closely to be certain the entire dose has been consumed.

Dogs & Cats: The duration of treatment should be selected based on clinical evidence.

Generally, administration of Baytril Tablets should continue for at least 2-3 days beyond cessation of clinical signs. For severe and/or complicated infections, more prolonged therapy, up to 30 days, may be required. If no improvement is seen within five days, the diagnosis should be reevaluated and a different course of therapy considered.

The lower limit of the dose range in dogs and the daily dose for cats was based on efficacy studies in dogs and cats where enrofloxacin was administered at 2.5 mg/kg twice daily. Target animal safety and toxicology were used to establish the upper limit of the dose range for dogs and treatment duration for dogs and cats.

Bayer Healthcare Llc Animal Health Division

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Bayer Healthcare Llc Animal Health Division Drugs